I'm going to start from the front with my data again, I hope DVap's numbers are off, or he is misinterpreting the test somehow. With the Nymox urine test I don't know why he is finding the need to do the multiplier to convert it to plasma testing, I think the test is what it is. So will go back a re-read the data, and the directive from Nymox.
I have work to do so don't know when I'll have time to dig into it again...but will do my best for a timely answer to this.
Edit: Question for DVap: have you read this PDF from Nymox. Be glad to send it to you, it's pretty big to put in a post, but follows is a preamble to setting up the test saliva tests, 2002.
Martin J. Jarvis, Paola Primatesta, Bob Erens, Colin Feyerabend,
Andrew Bryant
[Received 10 June 2002; accepted 1 October 2002]
Both plasma and saliva cotinine levels have been reported in surveys of smoking behavior, and it is of interest to know how closely these two measures correspond. Plasma and saliva specimens were gathered from a sample of 605 respondents in the 1998 Health Survey for England and assayed for cotinine by a well-proven gas chromatographic method. Plasma and saliva cotinine concentrations were highly correlated (r~.99). On average, concentrations in
saliva were 25% higher than in plasma, and this ratio applied both at the low levels attributable to passive smoking and across the range of active smoking values. The ratio was somewhat lower in younger people than in older people and also varied significantly by body mass index but did not differ by gender. Calculation of the limits of agreement
revealed substantial uncertainty in the predicted plasma value corresponding to a given saliva cotinine, and vice versa. For comparisons across subjects, the mean plasma cotinine level corresponding to a mean saliva cotinine level can be estimated with confidence, but at the level of the individual, considerable predictive uncertainty remains.
The difference between urine anaysis and saliva/plasma:
Testing Cotinine in Saliva vs. Urine
Some metabolites like cotinine, become concentrated in urine, compared to levels found in saliva. Because of this, a reading of 1 (6-30 ng/ml) for example, would normally indicate far more nicotine exposure if read from the saliva test, than from the urine test.
There is no fixed ratio of nicotine exposure when comparing urine to saliva readings (unless both tests have been performed on the same subject at the same time). The ratio of cotinine in saliva, to that found in urine, could vary between individuals, gender, or the time that has passed since the nicotine was ingested.
May
I do believe the Nymox Urine test is already correlated with saliva/plasma. Will look further to verify that, but as you can see, there is a formula applied to the Nymox Urine testing strip to correlate metabolised cotinine between urine, saliva, plasma (the latter two are usually assumed to be a ratio of 1:1, +/- 25%) These PDF files came directly from the Nymox Corporation, I can write again to clarify, however the gentleman I corresponded with sort of gave me the above on the 'side' so to speak. It is company info.
As stated,
I did both tests, Urine and Saliva, for my last test, and the data was the same, Level 3. Just for what it's worth.
Also, just now did another saliva test, Level 3 and holding!! 12mg/ml, using 1.5-3ml per day, Janty Stick 801 atty. Test level of cotinine is 100-200ng/ml. Works for me!! Over 1 year vaping. As stated, my cotinine level while smoking would have been right around 4000ng/ml, according to commonly agreed charts.
Now, for the sake of argument, I am using about 1/20th or 5% of nicotine vaping vs smoking say 3 packs of cigarettes, just to narrow things to an acceptable +/-. So am in effect consuming the equivalent to 3 cigarettes worth of nicotine???? If this theory is acceptable, that's fine with me, now take away all the toxins, poisons, and carcinogens and leave me with my CLEAN nicotine!!
DVap, feel free to interject, I run a pretty simple mind here. (To be kind, a non-formally-trained one!)
Also, in the interest of staving off effects of dementia or alzheimer's, and keeping my ADD afflicted thinking sharp and focused, I am figuring on holding this level for the rest of my days, hell or high water.
Click on pic to enlarge. Also note, there is color showing at the one and two levels, but the first "bar" is at level three, which may be indicative of a lower test (closer to 100 than 200ng cotinine.) Now, I gotta clean my scanner!!
)
