I wanted to comment on this responsible upfront snippet from the vapelicious website:
"You should note that WTA, like all electronic cigarettes are not a cessation product. A few people who use strong painkillers or other anti-depressants have claimed that the relaxation effect is extra strong, so please consult your doctor before trying WTA. Regular users haven’t reported this effect, but it sounds similar to the feeling when we have tried up to triple the strength which is sold."
Smoking itself has some of this type of effect for sure from my research. Certain less common tobaccos produce these effects quite strongly, even on their own. Even roll your own
tobacco has more mao inhibition (and thus wta's in likelyhood) than factory pre-rolled.
Snus has been shown in studies, and consumer experience to produce more overall non-nicotine alkaloids in the urine, than smoking (but effect itself seems to be released over time, instead of all at once vs smoking).
vaping wta is IMO probably very comparible to snus, effects/mao-i wise, if I was to stab a guess guess.
This sort of interaction, if its "something", is probably only occuring with very broad spectrum anti-depressants and very strong pain medication etc. It could be related to lack of tolerance to wta's etc
(I really wouldnt discount this entirely, lack of tolerance, re: these scattered reports either. When not smoking, a single cig hits you quite hard. That effect could be a lot stronger on heavy drugs where the effects are synergistic, and made worse by a nic-only vapers instinct to hit the PV harder than a cig. Imagine popping a strong snus, when ud only been using nic gum, in this circumstance. This is a theory worth consideration too IMO. I imagine all these folks tried a puff here and there and found it too much. Its hard to say if they had established tolerance, like a smoker, if the same thing would have occured)
And if you use WTA less frequently or in a lower mix, this might not apply so much- all kinda guessing .....but...
....
But for now I would echo this statement, and suggest just to be on the totally cautious side - if you use WTA
e-liquids, specially a stronger mix of WTA frequently and you see your doctor, or are prescribed a medicine - tell them you are using WTAs, and explain that it is a _mild_ mao inhibitor extracted from tobacco.
(If they ask for details, its both mao-a and b and reiterate that its mild -only people on heavy drugs like strong opiates have noticed anything at all, and then just basically feeling sleepy)
They wont know what a wta is, or about the minor alkaloids in tobacco (anabasine is a good one to give them if they want to look it up), but they'll know what a mao inhibitor is for sure. So theres there point of academic understanding.
In practice all this most likely means (if it indeed means anything!) is that for some using people using lots of WTA, you may need a little lower doses when using certain medicines (or at least being aware of some level of interaction, however small)- basically a little awareness on your medical professionals side cant hurt right?
And I know, that even chain smoking can make u a bit sleepy, especially on heavy sedative drugs, and its really as much speculation, caution and hearsay but just thought id say, it might be smart to bring it up with ur doc, just like anything else that might or might not be relevant to their work and your health.
Peace,
Drael
