In another Nautilus Mini thread, I wrote the following paragraphs about cleaning and priming a leaking Nautilus Mini tank. Some of the steps about priming may be useful to you.
The Nautilus Mini is a great tank--it is the only tank that helped me give up the smokes. I think you should dump the juice that's in it, completely disassemble the tank (including removing the glass cylinder from the chimney), toss the coil, rinse everything under running water. Do not try to dry everything with a towel, instead just shake off the water drops and blow out the base (the part the coil screws into). Carefully investigate the glass for small line-cracks, and then check the silicone gaskets anything that could case leaking (cuts, tears, burs, and the like).
If everything looks good, screw a new coil into the base. Apply a small drop of juice to one of the juice holes on the side of the coil. Watch it to be sure the juice gets absorbed through the hole into the cotton. Continue this procedure, going from hole to hole until the juice absorption slows down. Now, get some juice on your finger and rub it onto the big silicone gasket on the base. Also, rub a tiny bit of juice along the top of the glass cylinder and then screw the glass cylinder into the chimney. The glass cylinder should be tight, but not so much to break the glass. Fill the glass cylinder with new juice and then screw on the base. When tightening the base, I like to grasp the airflow control ring and tighten until the airflow control ring starts popping from setting to setting to setting--so I use the airflow control ring as a "torque gauge."
With the tank now assembled, turn the tank upright and give it a few draws without pushing the power button. Watch for bubbles rising within the tank, and listen for any signs of wetness as you draw air through the tank. After this, let the tank sit for at least a couple of minutes. When I first fire the tank, I give short pulses of the power button while drawing air through the tank, kind of like puffing on a cigar. Once I'm convinced the tank is working correctly, I then begin vaping. As the coil breaks in, I may increase my power setting to higher levels, especially if the tank begin gurgling.
The power setting to start vaping with, of course, is up to you. I generally start with 13 watts and then go upwards from there. For me, at power levels below 10-12 watts the Nautilus gives me unsatisfactory performance.