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Impact of tobacco use in patients presenting to a multidisciplinary
outpatient treatment program for fibromyalgia.
Clin J Pain. 2009 Jan;25(1):39-43.
Weingarten TN, Podduturu VR, Hooten WM, Thompson JM, Luedtke CA, Oh TH.
Departments of Anesthesiology and Physical Medicine and
Rehabilitation, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
<weingarten.toby_at_mayo.edu>
PMID: 19158544
OBJECTIVES: This study examined the relationship between the severity
of fibromyalgia symptoms and current tobacco use in patients
evaluated at a specialized fibromyalgia treatment program.
METHODS: Demographic and clinical data from 984 consecutive patients
evaluated at the Mayo Clinic Fibromyalgia Treatment Program including
the Fibromyalgia Impact Questionnaire (FIQ) were prospectively
collected and stored in an electronic medical record and an
electronic database. Univariate analyses were performed comparing
tobacco users and nonusers. A post-hoc analysis of covariance was
conducted for tobacco use, using group differences of confounding
clinical and demographic variables. A P value < or = 0.05 was
accepted as the level of significance.
RESULTS: One hundred and forty-five patients were identified as
tobacco users (14.7%). Tobacco use was associated with greater pain
intensity as measured by pain scales and the pain component of the
FIQ. Tobacco users had a greater FIQ composite score 70.0(15.1)
versus 61.8(16.8), P<0.001. By univariate analysis, tobacco users had
higher scores on all the FIQ components and fewer good days and more
days of work missed per week. Tobacco use was associated with several
confounding clinical and demographic variables including lower
education, higher unemployment, not being married or widowed, and
history of abuse. After adjusting for these confounding variables,
tobacco users continued to have greater pain intensity, a higher
total and component FIQ scores except for fatigue. Smoking was not
associated with a higher number of tender points.
DISCUSSION: Current tobacco use was associated with more severe
fibromyalgia symptoms in patients presenting to a specialized
fibromyalgia treatment program."
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