Established List of the Chemicals and Chemical Compounds Identified by FDA as Harmful and Potentially Harmful Constituents in tobacco Products and tobacco Smoke
Carcinogen (CA), Respiratory Toxicant (RT), Cardiovascular Toxicant (CT), Reproductive or Developmental Toxicant (RDT), Addictive (AD)
1,3-Butadiene CA, RT, RDT
1-Aminonaphthalene CA
2,6-Dimethylaniline CA
2-Aminonaphthalene CA
2-Nitropropane CA
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) CA
4-Aminobiphenyl CA
5-Methylchrysene CA
A-α-C (2-Amino-9H-pyrido[2,3-b]indole) CA
Acetaldehyde CA, RT, AD
Acetamide CA
Acetone RT
Acrolein RT, CT
Acrylamide CA
Acrylonitrile CA, RT
Aflatoxin B1 CA
Ammonia RT
Anabasine AD
Arsenic CA, CT, RDT
Benz[a]anthracene CA, CT
Benz[j]aceanthrylene CA
Benzene CA, CT, RDT
Benzo[a]pyrene CA
Benzofluoranthene CA, CT
Benzofuran CA
Benzo[c]phenanthrene CA
Benzo[k]fluoranthene CA, CT
Beryllium CA
Cadmium CA, RT, RDT
Caffeic acid CA
Carbon monoxide RDT
Catechol CA
Chlorinated dioxins/furans CA, RDT
Chromium CA, RT, RDT
Chrysene CA, CT
Cobalt CA, CT
Coumarin Banned in food
Cresols (o-, m-, and p-cresol) CA, RT
Crotonaldehyde CA
Cyclopenta[c,d]pyrene CA
Dibenz[a,h]anthracene CA
Dibenzo[a,e]pyrene CA
Dibenzo[a,h]pyrene CA
Dibenzo[a,i]pyrene CA
Dibenzo[a,l]pyrene CA
Ethyl carbamate (urethane) CA, RDT
Ethylbenzene CA
Ethylene oxide CA, RT, RDT
Formaldehyde CA, RT
Furan CA
Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole) CA
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) CA
Hydrazine CA, RT
Hydrogen cyanide RT, CT
Indeno[1,2,3-cd]pyrene CA
IQ (2-Amino-3-methylimidazo[4,5-f]quinoline) CA
Isoprene CA
Lead CA, CT, RDT
MeA-α-C (2-Amino-3-methyl)-9H-pyrido[2,3-b]indole) CA Mercury CA, RDT
Methyl ethyl ketone RT
N-Nitrosodiethanolamine (NDELA) CA
N-Nitrosodiethylamine CA
N-Nitrosodimethylamine (NDMA) CA
N-Nitrosomethylethylamine CA
N-Nitrosomorpholine (NMOR) CA
N-Nitrosonornicotine (NNN) CA
N-Nitrosopiperidine (NPIP) CA
N-Nitrosopyrrolidine (NPYR) CA
N-Nitrososarcosine (NSAR) CA
Naphthalene CA, RT
Nickel CA, RT
Nicotine RDT, AD
Nitrobenzene CA, RT, RDT
Nitromethane CA
Nornicotine AD
o-Anisidine CA
o-Toluidine CA
Phenol RT, CT
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) CA
Polonium-210 CA
Propionaldehyde RT, CT
Propylene oxide CA, RT
Quinoline CA
Selenium RT
Styrene CA
Toluene RT, RDT
Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole) CA
Trp-P-2 (1-Methyl-3-amino-5H-pyrido[4,3-b]indole ) CA
Uranium-235 CA, RT
Uranium-238 CA, RT
Vinyl acetate CA, RT
Vinyl chloride CA
Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke: Established List