For the hardware side - the eGo setup seems to be highly recommended here (and popular on many other sites too) as a good place to start. Battery life is good for many hours and the e-tank cartomizers are big enough to hold just over 1ml of e-juice compared to the slim cigarette type that usually only hold a few drops. That's big enough to get a good feel of vaping and taste of the particular juice you have without wasting a lot in some huge tank. Should you decide you want to go to a bigger, or smaller cartomizer, tank or clearomizer, there are many that are made to fit the eGo batteries. So they are very versatile. I have three now. Two 650mAh that I picked up locally and one eGo-C Twist 1000mAh that I ordered later. The Twist is nice because, not only do you get longer life from the 1000mAh, you can also adjust the the voltage to just the right spot for a particular cartomizer and/or juice.
On the e-juice/e-liquid side, things you need to think about here are: vapor vs throat hit, the amount of Nicotine added, and flavoring you like. You'll hear a lot said about VG and PG mixes. For a good explanation of these terms check out this site.
What does pg vg mean? What kind of e-liquid do i order?
You can also get an idea of what others like to vape by checking out the poll done here:
What pg vg ratio do you like best?
After you have an idea of some flavors you think you might like, I suggest checking out a place like
Mt. Baker Vapor that allow you to choose the ratio you'd like to try. Also, go with the smaller bottles first until you find one you like. If you'd like to stay with a tobacco taste, you might like the RY4 juice - it's a caramel/vanilla/tobacco blend. One of my favs, btw.
Hope this helps.
Chak