Yes, synthetic nicotine would likely show up as nicotine in a blood test. Synthetic nicotine refers to nicotine that is produced artificially rather than being extracted from
tobacco plants. However, the chemical structure of synthetic nicotine is identical to that of naturally derived nicotine, and both forms of nicotine would be metabolized in the body in the same way.
When nicotine is metabolized, it gets converted into various metabolites, including cotinine. Cotinine is one of the main metabolites of nicotine and is commonly used as a marker to assess nicotine exposure and usage. Whether nicotine comes from natural sources (like tobacco) or synthetic sources, the body's metabolic processes treat them the same way, resulting in the same metabolites being produced.
Therefore, in a blood test designed to detect nicotine or its metabolites, it would be challenging to distinguish between nicotine from synthetic sources and nicotine from natural sources. Both would likely result in the presence of cotinine or other related metabolites in the bloodstream, indicating nicotine consumption.