Eucalyptus oil in E-Liquid

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favor1

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I've been reading about Eucalyptus oil lately and it seems to be very good for inhalation (e.g. relieves sinus congestion, loosens phlegm, and many other small health bonuses). Does anyone have any experience with using Eucalyptus oil and if so, what are your thoughts on it? Also, eucalyptus oil would seem to be a very good additive to e-liquid as some of the ingredients (don't remember if it was PG or VG, or possibly other types of oils) build up as phlegm in your respiratory tract after vaping and have to be expelled; since eucalyptus oil loosens the phlegm, it should be a perfect additive, that is if tastes good too.

It seems to be a potent anti-biotic as well. According to the following sources (pulled of the Wikipedia), "

The cineole-based oil is used as component in pharmaceutical preparations to relieve the symptoms of influenza and colds, in products like cough sweets, lozenges, ointments and inhalants. Eucalyptus oil has antibacterial effects on pathogenic bacteria in the respiratory tract. Inhaled eucalyptus oil vapor is a decongestant and treatment for bronchitis. Cineole controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptus oil also stimulates immune system response by effects on the phagocytic ability of human monocyte derived macrophages. Eucalyptus oil also has anti-inflammatory and analgesic qualities as a topically applied liniment ingredient. Eucalyptus oil is also used in personal hygiene products for antimicrobial properties in dental care and soaps. It can also be applied to wounds to prevent infection."

and regarding usage:

If consumed internally at low dosage as a flavouring component or in pharmaceutical products at the recommended rate, cineole based 'oil of eucalyptus' is safe for adults. However, systemic toxicity can result from ingestion or topical application at higher than recommended doses. The probable lethal dose of pure eucalyptus oil for an adult is in the range of 0.05 mL to 0.5 mL/per kg of body weight [aka 4-40 ml for an 80 kg adult, which seems perfectly fine since eucalyptus is very potent and only a tiny amount would be added to e-liquid if all the theory works]. Because of their high body surface area to mass ratio, children are more vulnerable to poisons absorbed transdermally. Severe poisoning has occurred in children after ingestion of 4 mL to 5 mL of eucalyptus oil.

Salari, M. H., Amine, G., Shirazi, M. H., Hafezi, R., and Mohammadypour, M. “Antibacterial effects of Eucalyptus globulus leaf extract on pathogenic bacteria isolated from specimens of patients with respiratory tract disorders.” Clin Microbiol.Infect. 2006;12(2):194-196

Lu XQ, Tang FD, Wang Y, Zhao T, Bian RL, Effect of Eucalyptus globulus oil on lipopolysaccharide-induced chronic bronchitis and mucin hypersecretion in rats, Zhongguo Zhong Yao Za Zhi, 2004 Feb;29(2):168-71.

Juergens, U. et al., Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial, Respiratory Medicine, 2003, Vol. 97, Iss. 3, pp250 - 256.

Juergens, U., Engelen, T., Racké, K., Stöber, M., Gillissen, A., Vetter, H., Inhibitory activity of 1,8-cineol (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes, Pulmonary Pharmacology & Therapeutics, 2004, Vol. 17 , Iss. 5, pp281 - 287

Serafino, A., Vallebona, P.S., Andreola, F., Zonfrillo, M., Mercuri, L., Federici, M., Rasi, G., Garaci, E., and Pierimarchi, P., Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response, BMC Immunol. 2008; 9: 17.

Göbel, H., Schmidt, G., Soyka, D., Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters, Cephalalgia, Vol. 14, Iss. 3, pp228 - 234

Hong, C-Z., Shellock, F.G., Effects of a topically applied counterirritant (Eucalyptmint) on cutaneous blood flow and on skin and muscle temperatures: a placebo-controlled study, American Journal of Physical Medicine & Rehabilitation 70(1):29-33, February 1991

Nagata, H., Inagaki, Y., Tanaka, M., Ojima, M., Kataoka, K., Kuboniwa, M., Nishida, N., Shimizu, K., Osawa, K., and Shizukuishi, S., "Effect of Eucalyptus Extract Chewing Gum on Periodontal Health: A Double-Masked, Randomized Trial", Journal of Periodontology, 2008, Vol. 79, No. 8, pp1378-1385.


Thank you for your thoughts.

Edit: Also, it seems safe to ingest as well; a lot of drinkable herbal medicines contain eucalyptus in small amounts and there are martini recipes containing eucalyptus:

http://cocktails.about.com/od/mixol...-in-Mixology/Eucalyptus-Herb-in-Cocktails.htm
 
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zoiDman

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and regarding usage:

If consumed internally at low dosage as a flavouring component or in pharmaceutical products at the recommended rate, cineole based 'oil of eucalyptus' is safe for adults. However, systemic toxicity can result from ingestion or topical application at higher than recommended doses.

I think this is a Key Concept that is overlooked by many people when considering Flavoring Safety.

Most Flavorings were not Engineered to be Vaporized and then Inhaled Constantly over a Long period time.

Is Eucalyptus Oil safe to vape Daily? I dunno.

Personaly I don't use Any Oil Based Flavorings.
 
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favor1

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I think this is a Key Concept that is overlooked by many people when considering Flavoring Safety.

Most Flavorings were not Engineered to be Vaporized and then Inhaled Constantly over a Long period time.

Is Eucalyptus Oil safe to vape Daily? I dunno.

Personaly I don't use Any Oil Based Flavorings.

That's what I would think as well, but Eucalyptus oil is being vaporized and used as an inhalant already for medicinal purposes so there shouldn't be any adverse effects if used in moderation. Regarding solubility, increasing the PG percentage should fix any issues.
 
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